Variations of serum calcium profile among Premenopausal and Postmenopausal Women in Gezira state, Sudan

الملخص

Oestrogen deficiency after menopause, as well as age-related processes, alters
the rate of calcium resorption in bone and causes of bone loss in postmenopausal
women. Our present study aim to compare serum calcium status in premenopausal and postmenopausal women. The study was a cross sectional study
was done in a Gezira State, Sudan. Among female their means age were (23.73
± 11.32 years) of pre-menopausal and (55.07 ± 5.67years) post postmenopausal
women. Three ml of blood was collected in heparin vacuum tubes and serum
calcium was measured by Calcium-O-Cresolphthalein Complexone colorimetric
method. SPSS version 23 was used for data analysis. P value > 0.05 was
considered statistically significant. The results showed that there was significant
difference in mean age (23.73 11.32 years vs. 55.07 5.67 years), weight (62.49
17.13kg vs. 69.32 16.47kg), and body mass index (23.443.16 vs. 27.53 4.21)
p<0.05 between premenopausal women and postmenopausal women, but there
was no significant different in their height (161.62±0.38Cm vs.
158.70±0.13Cm). Serum calcium showed significantly reduced in
postmenopausal women 8.6± 0.64 mg/dl compared to the premenopausal
women values10.37± 0.69mg/dl, (P=0.03). However, serum calcium level in  both group found to be within the normal reference range. This study concluded
that the postmenopausal women in Al Gezira State had lower mean values of
serum calcium but within the normal serum reference values.